L27P (p.Leu27Pro) variant of F13A1 (Coagulation factor XIII A chain)
L27P (p.Leu27Pro) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L27P (p.Leu27Pro) variant details
- p.Leu27Pro
- ExAC rs781705895
- TOPMed rs781705895
- gnomAD rs781705895
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.39
- MetaLR 0.17
- MetaSVM -0.91
- CADD 16.00
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.5e-05)
- Structural context available