I76T (p.Ile76Thr) variant of F13A1 (Coagulation factor XIII A chain)
I76T (p.Ile76Thr) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
I76T (p.Ile76Thr) variant details
- p.Ile76Thr
- ExAC rs775876960
- TOPMed rs775876960
- gnomAD rs775876960
- Missense
- Variant Prioritization Score for Impact Estimate 0.795
- REVEL 0.89
- MetaLR 0.80
- MetaSVM 0.76
- CADD 26.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available