I122V (p.Ile122Val) variant of F13A1 (Coagulation factor XIII A chain)
I122V (p.Ile122Val) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
I122V (p.Ile122Val) variant details
- p.Ile122Val
- ESP rs142064728
- ExAC rs142064728
- gnomAD rs142064728
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.18
- MetaLR 0.10
- MetaSVM -0.97
- CADD 0.72
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available