I118T (p.Ile118Thr) variant of F13A1 (Coagulation factor XIII A chain)
I118T (p.Ile118Thr) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
I118T (p.Ile118Thr) variant details
- p.Ile118Thr
- ExAC rs759210544
- gnomAD rs759210544
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.80
- MetaLR 0.74
- MetaSVM 0.60
- CADD 26.50
- PolyPhen-2 0.65
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available