G34V (p.Gly34Val) variant of F13A1 (Coagulation factor XIII A chain)
G34V (p.Gly34Val) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G34V (p.Gly34Val) variant details
- p.Gly34Val
- ExAC rs778222128
- TOPMed rs778222128
- gnomAD rs778222128
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.35
- MetaLR 0.29
- MetaSVM -0.67
- CADD 19.40
- PolyPhen-2 0.22
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available