G115R (p.Gly115Arg) variant of F13A1 (Coagulation factor XIII A chain)
G115R (p.Gly115Arg) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G115R (p.Gly115Arg) variant details
- p.Gly115Arg
- ExAC rs763649812
- TOPMed rs763649812
- gnomAD rs763649812
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.61
- MetaLR 0.72
- MetaSVM 0.53
- CADD 25.20
- PolyPhen-2 0.62
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available