F9S (p.Phe9Ser) variant of F13A1 (Coagulation factor XIII A chain)
F9S (p.Phe9Ser) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
F9S (p.Phe9Ser) variant details
- p.Phe9Ser
- TOPMed rs919588838
- gnomAD rs919588838
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.37
- MetaLR 0.36
- MetaSVM -0.56
- CADD 23.10
- PolyPhen-2 0.24
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available