F45L (p.Phe45Leu) variant of F13A1 (Coagulation factor XIII A chain)
F45L (p.Phe45Leu) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
F45L (p.Phe45Leu) variant details
- p.Phe45Leu
- gnomAD rs1172080141
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.18
- MetaLR 0.12
- MetaSVM -0.93
- CADD 14.30
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available