D25G (p.Asp25Gly) variant of F13A1 (Coagulation factor XIII A chain)
D25G (p.Asp25Gly) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D25G (p.Asp25Gly) variant details
- p.Asp25Gly
- TOPMed rs1359737567
- gnomAD rs1359737567
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.25
- MetaLR 0.01
- MetaSVM -0.96
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available