Y115C (p.Tyr115Cys) variant of F11 (Coagulation factor XI)
Y115C (p.Tyr115Cys) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
Y115C (p.Tyr115Cys) variant details
- p.Tyr115Cys
- TOPMed rs1241701325
- gnomAD rs1241701325
- Missense
- Variant Prioritization Score for Impact Estimate 0.645
- REVEL 0.58
- ESM-1b 1.00
- AlphaMissense 0.28
- MetaLR 0.89
- MetaSVM 0.51
- CADD 22.90
- Population evidence available
- Structural context available