W73G (p.Trp73Gly) variant of F11 (Coagulation factor XI)
W73G (p.Trp73Gly) in F11 (Coagulation factor XI) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes structural context.
W73G (p.Trp73Gly) variant details
- p.Trp73Gly
- TOPMed rs896571623
- gnomAD rs896571623
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.45
- ESM-1b 0.00
- AlphaMissense 0.10
- MetaLR 0.68
- MetaSVM 0.06
- CADD 19.45
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available