V49D (p.Val49Asp) variant of F11 (Coagulation factor XI)
V49D (p.Val49Asp) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
V49D (p.Val49Asp) variant details
- p.Val49Asp
- TOPMed rs1249898354
- gnomAD rs1249898354
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.62
- ESM-1b 1.00
- AlphaMissense 0.43
- MetaLR 0.76
- MetaSVM 0.59
- CADD 22.70
- Population evidence available
- Structural context available