T28I (p.Thr28Ile) variant of F11 (Coagulation factor XI)
T28I (p.Thr28Ile) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T28I (p.Thr28Ile) variant details
- p.Thr28Ile
- cosmic curated COSV11289
- ExAC rs775977740
- gnomAD rs775977740
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.32
- MetaSVM -0.76
- CADD 1.09
- Population evidence available
- Structural context available