T22I (p.Thr22Ile) variant of F11 (Coagulation factor XI)
T22I (p.Thr22Ile) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T22I (p.Thr22Ile) variant details
- p.Thr22Ile
- ExAC rs760244383
- gnomAD rs760244383
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.12
- MetaLR 0.51
- MetaSVM -0.40
- CADD 13.58
- Population evidence available
- Structural context available