T150A (p.Thr150Ala) variant of F11 (Coagulation factor XI)
T150A (p.Thr150Ala) in F11 (Coagulation factor XI) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes structural context.
T150A (p.Thr150Ala) variant details
- p.Thr150Ala
- rs1740201176
- ClinGen CA358958670
- ClinVar RCV001810671
- Ensembl rs1740201176
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- REVEL 0.77
- ESM-1b 1.00
- AlphaMissense 0.41
- MetaLR 0.88
- MetaSVM 0.98
- CADD 22.60
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available