S81I (p.Ser81Ile) variant of F11 (Coagulation factor XI)
S81I (p.Ser81Ile) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
S81I (p.Ser81Ile) variant details
- p.Ser81Ile
- ExAC rs766388775
- gnomAD rs766388775
- Missense
- Variant Prioritization Score for Impact Estimate 0.801
- REVEL 0.87
- ESM-1b 1.00
- AlphaMissense 0.48
- MetaLR 0.85
- MetaSVM 0.89
- CADD 25.10
- Population evidence available
- Structural context available