R88I (p.Arg88Ile) variant of F11 (Coagulation factor XI)
R88I (p.Arg88Ile) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R88I (p.Arg88Ile) variant details
- p.Arg88Ile
- cosmic curated COSV99251
- ExAC rs755446937
- TOPMed rs755446937
- gnomAD rs755446937
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.27
- ESM-1b 0.18
- AlphaMissense 0.11
- MetaLR 0.45
- MetaSVM -0.58
- CADD 12.73
- Population evidence available
- Structural context available