R154K (p.Arg154Lys) variant of F11 (Coagulation factor XI)
R154K (p.Arg154Lys) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R154K (p.Arg154Lys) variant details
- p.Arg154Lys
- ESP rs369850780
- ExAC rs369850780
- TOPMed rs369850780
- gnomAD rs369850780
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.12
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.38
- MetaSVM -0.79
- CADD 3.96
- Population evidence available
- Structural context available