L78P (p.Leu78Pro) variant of F11 (Coagulation factor XI)
L78P (p.Leu78Pro) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.88 / 1. The record also includes population frequency data and structural context.
L78P (p.Leu78Pro) variant details
- p.Leu78Pro
- gnomAD rs1373928760
- Missense
- Variant Prioritization Score for Impact Estimate 0.882
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.92
- MetaLR 0.90
- MetaSVM 1.02
- CADD 27.10
- Population evidence available
- Structural context available