L78M (p.Leu78Met) variant of F11 (Coagulation factor XI)
L78M (p.Leu78Met) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L78M (p.Leu78Met) variant details
- p.Leu78Met
- gnomAD rs1173237540
- Missense
- Variant Prioritization Score for Impact Estimate 0.664
- REVEL 0.60
- ESM-1b 0.98
- AlphaMissense 0.27
- MetaLR 0.86
- MetaSVM 0.83
- CADD 23.70
- Population evidence available
- Structural context available