I114T (p.Ile114Thr) variant of F11 (Coagulation factor XI)
I114T (p.Ile114Thr) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
I114T (p.Ile114Thr) variant details
- p.Ile114Thr
- ExAC rs774468455
- gnomAD rs774468455
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.42
- ESM-1b 0.70
- AlphaMissense 0.10
- MetaLR 0.77
- MetaSVM -0.21
- CADD 15.11
- Population evidence available
- Structural context available