H105Y (p.His105Tyr) variant of F11 (Coagulation factor XI)
H105Y (p.His105Tyr) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
H105Y (p.His105Tyr) variant details
- p.His105Tyr
- gnomAD rs1453551656
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.34
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.69
- MetaSVM 0.06
- CADD 16.87
- Population evidence available
- Structural context available