H105R (p.His105Arg) variant of F11 (Coagulation factor XI)
H105R (p.His105Arg) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes structural context.
H105R (p.His105Arg) variant details
- p.His105Arg
- TOPMed rs1740107120
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.29
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.65
- MetaSVM -0.13
- CADD 16.80
- Structural context available