G18D (p.Gly18Asp) variant of F11 (Coagulation factor XI)
G18D (p.Gly18Asp) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
G18D (p.Gly18Asp) variant details
- p.Gly18Asp
- ExAC rs774959355
- TOPMed rs774959355
- gnomAD rs774959355
- Missense
- Variant Prioritization Score for Impact Estimate 0.557
- REVEL 0.63
- ESM-1b 0.62
- AlphaMissense 0.11
- MetaLR 0.64
- MetaSVM -0.23
- CADD 14.84
- Population evidence available
- Structural context available