F156L (p.Phe156Leu) variant of F11 (Coagulation factor XI)
F156L (p.Phe156Leu) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
F156L (p.Phe156Leu) variant details
- p.Phe156Leu
- 1000Genomes rs142929551
- ExAC rs142929551
- TOPMed rs142929551
- gnomAD rs142929551
- Missense
- Variant Prioritization Score for Impact Estimate 0.683
- REVEL 0.59
- ESM-1b 1.00
- AlphaMissense 0.91
- MetaLR 0.81
- MetaSVM 0.80
- CADD 23.70
- Population evidence available
- Structural context available