C76S (p.Cys76Ser) variant of F11 (Coagulation factor XI)
C76S (p.Cys76Ser) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
C76S (p.Cys76Ser) variant details
- p.Cys76Ser
- ExAC rs758461048
- gnomAD rs758461048
- Missense
- Variant Prioritization Score for Impact Estimate 0.87
- REVEL 0.88
- ESM-1b 1.00
- AlphaMissense 0.95
- MetaLR 0.99
- MetaSVM 0.95
- CADD 26.80
- Population evidence available
- Structural context available