C76F (p.Cys76Phe) variant of F11 (Coagulation factor XI)
C76F (p.Cys76Phe) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.91 / 1. The record also includes structural context.
C76F (p.Cys76Phe) variant details
- p.Cys76Phe
- ExAC rs758461048
- gnomAD rs758461048
- Missense
- Variant Prioritization Score for Impact Estimate 0.913
- REVEL 0.96
- ESM-1b 1.00
- AlphaMissense 0.92
- MetaLR 1.00
- MetaSVM 0.93
- CADD 27.60
- Structural context available