C50S (p.Cys50Ser) variant of F11 (Coagulation factor XI)
C50S (p.Cys50Ser) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
C50S (p.Cys50Ser) variant details
- p.Cys50Ser
- 1000Genomes rs533298073
- Missense
- Variant Prioritization Score for Impact Estimate 0.847
- REVEL 0.84
- ESM-1b 1.00
- AlphaMissense 0.97
- MetaLR 1.00
- MetaSVM 0.96
- CADD 25.60
- Population evidence available
- Structural context available