C500W (p.Cys500Trp) variant of F11 (Coagulation factor XI)

C500W (p.Cys500Trp) in F11 (Coagulation factor XI) is a missense change. Clinical records from ClinVar and UniProt describe it as pathogenic/likely pathogenic in the context of Plasma factor XI deficiency; Hereditary factor XI deficiency disease. The record also includes population frequency data and structural context.

C500W (p.Cys500Trp) variant details