C20S (p.Cys20Ser) variant of F11 (Coagulation factor XI)
C20S (p.Cys20Ser) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
C20S (p.Cys20Ser) variant details
- p.Cys20Ser
- ExAC rs775930271
- gnomAD rs775930271
- Missense
- Variant Prioritization Score for Impact Estimate 0.772
- REVEL 0.73
- ESM-1b 1.00
- AlphaMissense 0.74
- MetaLR 0.94
- MetaSVM 1.05
- CADD 24.80
- Population evidence available
- Structural context available