C146R (p.Cys146Arg) variant of F11 (Coagulation factor XI)
C146R (p.Cys146Arg) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.92 / 1. The record also includes population frequency data and structural context.
C146R (p.Cys146Arg) variant details
- p.Cys146Arg
- ExAC rs761248034
- gnomAD rs761248034
- Missense
- Variant Prioritization Score for Impact Estimate 0.916
- REVEL 0.97
- ESM-1b 1.00
- AlphaMissense 0.95
- MetaLR 1.00
- MetaSVM 0.90
- CADD 25.70
- Population evidence available
- Structural context available