C103R (p.Cys103Arg) variant of F11 (Coagulation factor XI)
C103R (p.Cys103Arg) in F11 (Coagulation factor XI) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.88 / 1. The record also includes population frequency data and structural context.
C103R (p.Cys103Arg) variant details
- p.Cys103Arg
- ExAC rs773735877
- gnomAD rs773735877
- Missense
- Variant Prioritization Score for Impact Estimate 0.88
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.80
- MetaLR 0.92
- MetaSVM 1.05
- CADD 28.40
- Population evidence available
- Structural context available