V8L (p.Val8Leu) variant of F10 (Coagulation factor X)
V8L (p.Val8Leu) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V8L (p.Val8Leu) variant details
- p.Val8Leu
- ESP rs372884946
- ExAC rs372884946
- TOPMed rs372884946
- gnomAD rs372884946
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.17
- CADD 0.75
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available