T61S (p.Thr61Ser) variant of F10 (Coagulation factor X)
T61S (p.Thr61Ser) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
T61S (p.Thr61Ser) variant details
- p.Thr61Ser
- gnomAD 13-113129562-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.32
- MetaLR 0.85
- MetaSVM 0.52
- CADD 3.09
- PolyPhen-2 0.02
- SIFT 0.59
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available