T61A (p.Thr61Ala) variant of F10 (Coagulation factor X)
T61A (p.Thr61Ala) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
T61A (p.Thr61Ala) variant details
- p.Thr61Ala
- gnomAD 13-113129562-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.22
- MetaLR 0.88
- MetaSVM 0.53
- CADD 3.88
- PolyPhen-2 0.02
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available