S43F (p.Ser43Phe) variant of F10 (Coagulation factor X)
S43F (p.Ser43Phe) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
S43F (p.Ser43Phe) variant details
- p.Ser43Phe
- gnomAD 13-113129509-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.63
- MetaLR 0.99
- MetaSVM 0.98
- CADD 22.60
- PolyPhen-2 0.91
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available