S13C (p.Ser13Cys) variant of F10 (Coagulation factor X)
S13C (p.Ser13Cys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
S13C (p.Ser13Cys) variant details
- p.Ser13Cys
- gnomAD 13-113122893-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.37
- CADD 6.89
- PolyPhen-2 0.11
- SIFT 0.78
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available