S11C (p.Ser11Cys) variant of F10 (Coagulation factor X)
S11C (p.Ser11Cys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S11C (p.Ser11Cys) variant details
- p.Ser11Cys
- gnomAD 13-113122886-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.25
- CADD 0.27
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available