R55T (p.Arg55Thr) variant of F10 (Coagulation factor X)
R55T (p.Arg55Thr) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
R55T (p.Arg55Thr) variant details
- p.Arg55Thr
- gnomAD 13-113129545-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.834
- REVEL 0.87
- MetaLR 0.99
- MetaSVM 0.96
- CADD 24.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available