R55K (p.Arg55Lys) variant of F10 (Coagulation factor X)
R55K (p.Arg55Lys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
R55K (p.Arg55Lys) variant details
- p.Arg55Lys
- ExAC rs753080446
- TOPMed rs753080446
- gnomAD rs753080446
- Missense
- Variant Prioritization Score for Impact Estimate 0.765
- REVEL 0.81
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available