R3L (p.Arg3Leu) variant of F10 (Coagulation factor X)
R3L (p.Arg3Leu) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R3L (p.Arg3Leu) variant details
- p.Arg3Leu
- 1000Genomes rs1026200798
- TOPMed rs1026200798
- gnomAD rs1026200798
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.19
- CADD 7.95
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available