R3G (p.Arg3Gly) variant of F10 (Coagulation factor X)
R3G (p.Arg3Gly) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
R3G (p.Arg3Gly) variant details
- p.Arg3Gly
- gnomAD 13-113122862-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.15
- CADD 6.98
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available
- Literature evidence available