M58K (p.Met58Lys) variant of F10 (Coagulation factor X)
M58K (p.Met58Lys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
M58K (p.Met58Lys) variant details
- p.Met58Lys
- TOPMed rs1435923649
- gnomAD rs1435923649
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.37
- CADD 7.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available