L24P (p.Leu24Pro) variant of F10 (Coagulation factor X)
L24P (p.Leu24Pro) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
L24P (p.Leu24Pro) variant details
- p.Leu24Pro
- Ensembl rs372382600
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.64
- CADD 23.20
- PolyPhen-2 0.36
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available