L20P (p.Leu20Pro) variant of F10 (Coagulation factor X)
L20P (p.Leu20Pro) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L20P (p.Leu20Pro) variant details
- p.Leu20Pro
- ExAC rs756166351
- gnomAD rs756166351
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.23
- CADD 9.98
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available