L20F (p.Leu20Phe) variant of F10 (Coagulation factor X)
L20F (p.Leu20Phe) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L20F (p.Leu20Phe) variant details
- p.Leu20Phe
- gnomAD rs1178574775
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.20
- CADD 9.77
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available