L19Q (p.Leu19Gln) variant of F10 (Coagulation factor X)
L19Q (p.Leu19Gln) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L19Q (p.Leu19Gln) variant details
- p.Leu19Gln
- gnomAD 13-113122911-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.51
- CADD 9.26
- PolyPhen-2 0.17
- SIFT 0.66
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available