K50E (p.Lys50Glu) variant of F10 (Coagulation factor X)
K50E (p.Lys50Glu) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
K50E (p.Lys50Glu) variant details
- p.Lys50Glu
- ExAC rs766388026
- gnomAD rs766388026
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.60
- CADD 19.00
- PolyPhen-2 0.61
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available