H52Y (p.His52Tyr) variant of F10 (Coagulation factor X)
H52Y (p.His52Tyr) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
H52Y (p.His52Tyr) variant details
- p.His52Tyr
- ExAC rs755187056
- TOPMed rs755187056
- gnomAD rs755187056
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.34
- CADD 15.00
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available