G2R (p.Gly2Arg) variant of F10 (Coagulation factor X)
G2R (p.Gly2Arg) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
G2R (p.Gly2Arg) variant details
- p.Gly2Arg
- gnomAD 13-113122859-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.24
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available